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Disease name
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유전성 출혈성 모세혈관 확장(오슬러-웨버-렌두씨 병)
(Hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber disease))
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Study name
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전임상실험을 통한 '유전성 출혈성 모세혈관확장증'에 미치는 신생혈관억제제의 효과 검증 |
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Government department
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보건복지부 |
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Enterprise
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보건의료연구개발 |
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Institute
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가천의과대학 |
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Department
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분자생물학 |
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Duration
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2010-04-01~2012-03-31 |
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Director
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오석 |
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Email
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spauloh@hanmail.net |
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Contact
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032-899-6063 |
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References
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Generation of mice with a conditional and reporter allele for Tmem100. Moon EH, Kim MJ, Ko KS, Kim YS, Seo J, Oh SP, Lee YJ. Genesis. 2010 Nov;48(11):673-8. doi: 10.1002/dvg.20674. Epub 2010 Oct 30.
PMID:
20848592
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Spectral imaging reveals microvessel physiology and function from anastomoses to thromboses. Wankhede M, Agarwal N, Fraga-Silva RA, deDeugd C, Raizada MK, Oh SP, Sorg BS. J Biomed Opt. 2010 Jan-Feb;15(1):011111.
PMID:
20210437
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Biology of vascular malformations of the brain. Leblanc GG, Golanov E, Awad IA, Young WL; Biology of Vascular Malformations of the Brain NINDS Workshop Collaborators. Stroke. 2009 Dec;40(12):e694-702. Epub 2009 Oct 15. Review.
PMID:
19834013
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Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia. Park SO, Wankhede M, Lee YJ, Choi EJ, Fliess N, Choe SW, Oh SH, Walter G, Raizada MK, Sorg BS, Oh SP. J Clin Invest. 2009 Nov;119(11):3487-9
PMID:
19805914
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ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2. Park SO, Lee YJ, Seki T, Hong KH, Fliess N, Jiang Z, Park A, Wu X, Kaartinen V, Roman BL, Oh SP. Blood. 2008 Jan 15;111(2):633-42. Epub 2007 Oct
PMID:
17911384
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Activin receptor-like kinase 1 is essential for placental vascular development in mice. Hong KH, Seki T, Oh SP. Lab Invest. 2007 Jul;87(7):670-9. Epub 2007 May 28.
PMID:
17530030
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Isolation of a regulatory region of activin receptor-like kinase 1 gene sufficient for arterial endothelium-specific expression. Seki T, Hong KH, Yun J, Kim SJ, Oh SP. Circ Res. 2004 Apr 30;94(8):e72-7. Epub 2004 Apr 1.
PMID:
15059937
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Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling. Seki T, Yun J, Oh SP. Circ Res. 2003 Oct 3;93(7):682-9. Epub 2003 Sep 11.
PMID:
12970115
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A mouse model for hereditary hemorrhagic telangiectasia (HHT) type 2. Srinivasan S, Hanes MA, Dickens T, Porteous ME, Oh SP, Hale LP, Marchuk DA. Hum Mol Genet. 2003 Mar 1;12(5):473-82.
PMID:
12588795
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Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. Oh SP, Seki T, Goss KA, Imamura T, Yi Y, Donahoe PK, Li L, Miyazono K, ten Dijke P, Kim S, Li E. Proc Natl Acad Sci U S A. 2000 Mar 14;
PMID:
10716993
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